Inheritance of oral susceptibility of Aedes aegypti to Chikungunya virus
Autor(es): Mourya D T, Gokhale M D, Malunjkar A S, Bhat H R, Banerjee K
Resumo: A colony of rosy eye mutants of Aedes aegypti was established. This strain was refractory to Chikungunya virus by oral route of infection when compared with the wild-type parent strain. The refractoriness of this strain seems to be due to a mesentronal barrier, since both the mosquito strains supported the multiplication of virus after intrathoracic inoculation. The rosy eye strain was also found to be refractory to Sagiyama virus (Alphaviridae: Getah virus subtype) when compared with wild-type parent strain, but no such difference in the oral susceptibility was found with dengue-2 (Flaviviridae) virus. The rosy eye mutant appears to be closely linked to the gene(s) for refractoriness to alpha viruses - may be useful in future studies in underst-ing the genetic basis of vector competence of Ae. aegypti to arboviruses.
Imprenta: The American Journal of Tropical Medicine and Hygiene, v. 51, n. 3, p. 295-300, 1994
Identificador do objeto digital: 10.4269/ajtmh.1994.51.295
Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Genome ; Chikungunya virus - Pathogenesis ; Chikungunya Virus - Virus ; Chikungunya virus - Dengue ; Chikungunya virus - Immunology
Data de publicação: 1994
