Further study of spontaneous interferon produced by hamster peritoneal cells
Autor(es): Tálas M, Szolgay E, Rózsa K S
Resumo: Cells of peritoneal exudate of hamster have been found capable of "spontaneously" producing an inhibitor which suppresses virus multiplication in cell culture. Mobilization of macrophagesin vivo with starch inoculated into the peritoneal cavity slightly increased production of the inhibitor. Investigation of some biological, physical and chemical properties of the inhibitor demonstrated its similarity with interferon produced under the effect of endotoxin. The molecular weight of the inhibitor was 100,000. No effect of antimetabolites (actinomycin D and cycloheximide) on production of "spontaneous" interferon or responsibility of any latent virus of hamsters for its production could be demonstrated.
Imprenta: Archiv fu?r die gesamte Virusforschung, v. 38, n. 2, p. 149-158, 1972
Identificador do objeto digital: 10.1007/BF01249665
Descritores: Chikungunya virus - Biosynthesis ; Chikungunya virus - Cell ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Cytokines ; Chikungunya Virus - Virus
Data de publicação: 1972
