Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice
Autor(es): Giovarelli M, Viano I, Zucca M, Valbonesi R, Dianzani F
Resumo: Mice neonatally immunosuppressed with anti-mu antiserum failed to produce circulating antibodies to sheep erythrocytes - showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.
Imprenta: Infection and Immunity, v. 16, n. 3, p. 849-852, 1977
Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Biosynthesis ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology
Data de publicação: 1977
