Detection of Chikungunya virus in wild populations of Aedes albopictus in Kerala State, India
Autor(es): Kumar Narendran Pradeep, Sabesan Shanmugavelu, Krishnamoorthy Kaliannagounder, Jambulingam Purushothaman
Resumo: We detected Chikungunya virus (CHIKV) infection among wild populations of Aedes albopictus female specimens during the CHIKV outbreaks of 2009 - 2006 collected in different localities in Kerala State, India. The envelope 1 gene (E1) sequences of the virus isolate 2009 from the mosquito species showed close genetic relatedness (Kimura 2 Parameter genetic distance=0.0013) to CHIKV-positive isolates from human serum samples from the same area. E1 gene sequences from Ae. albopictus, as well as from human isolates, had the crucial non-synonymous C/T mutation at position 10670, leading to the A226V amino acid change. This natural inclination indicated the role of this mosquito species in the transmission of CHIKV during its recent outbreaks in Kerala State.
Imprenta: Vector Borne and Zoonotic Diseases, v. 12, n. 10, p. 907-911, 2012
Identificador do objeto digital: 10.1089/vbz.2012.0969
Descritores: Chikungunya virus - DNA ; Chikungunya virus - Molecular structure ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - RNA ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2012
