Dengue fever as an acute febrile disease after overseas travel: A report of two cases

Capa:Dengue fever as an acute febrile disease after overseas travel: A report of two cases

Autor(es): Tarumoto Norihito, Abe Yoshinobu, Yamaguchi Toshiyuki, Takasaki Tomohiko, Kurane Ichiro, Maesaki Shigefumi


Resumo: Dengue fever (DF) is a relatively common infection in travelers, with about 100 cases being reported annually in Japan, - this number is increasing. We herein describe two patients who developed a fever after returning to Japan from Southeast Asia - who were serologically diagnosed with DF. Patient 1 was a 19-year-old man who spent 6 days in Thail- - developed diarrhea - a fever after returning to Japan. Virological studies showed dengue virus (DV) serotype 3 by reverse transcriptase PCR (RT-PCR), - anti-DV IgM - IgG antibodies were both positive by enzyme-linked immunosorbent assay (ELISA). Patient 2 was a 43-year-old man who spent time in various Asian countries - developed a fever - arthralgia after returning to Japan. Virological studies showed DV serotype 2 by RT-PCR, - anti-DV IgM - IgG antibodies were both positive by ELISA. DF - other febrile diseases, including Chikungunya fever, should be strongly suspected in patients who develop fever after returning to Japan from other Asian countries, irrespective of whether patients remember being bitten by mosquitoes.


Imprenta: Japanese Journal of Infectious Diseases, v. 64, n. 2, p. 163-164, 2011


Descritores: Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - RNA ; Chikungunya virus - Antibodies ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Immunology


Data de publicação: 2011