Chikungunya virus infection during pregnancy, Reunion, France, 2006

Autor(es): Fritel Xavier, Rollot Olivier, Gerardin Patrick, Gauzere Bernard Alex, Bideault Jacques, Lagarde Louis, Dhuime Barbara, Orvain Eric, Cuillier Fabrice, Ramful Duksha, Samperiz Sylvain, Jaffar-B-jee Marie Christine, Michault Alain, Cotte Liliane, Kaminski Monique, Fourmaintraux Alain


Resumo: Mother-to-child transmission of chikungunya virus was reported during the 2005-2006 outbreak on Reunion Isl-, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Reunion in 2006. The study population was composed of 1,400 pregnant women (628 uninfected, 658 infected during pregnancy, 27 infected before pregnancy, - 87 infected on unknown dates). We compared pregnancy outcomes for 655 (628 + 27) women not infected during pregnancy with 658 who were infected during pregnancy. Infection occurred during the first trimester for 15% of the infected women, the second for 59%, - the third for 26%. Only hospital admission during pregnancy differed between infected - uninfected women (40% vs. 29%). Other outcomes (cesarean deliveries, obstetric hemorrhaging, preterm births, stillbirths after 22 weeks, birthweight, congenital malformations, - newborn admissions) were similar. This virus had no observable effect on pregnancy outcomes.


Imprenta: Emerging Infectious Diseases, v. 16, n. 3, p. 418-425, 2010


Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health


Data de publicação: 2010