Autor(es): Oh Han Boon, Muthu Vaishnavi, Daruwalla Zubin J, Lee Shir Ying, Koay Evelyn S, Tambyah Paul A

Resumo: Blood-borne infections remain a risk of blood transfusions. While routine screening of donated blood products has greatly reduced the risk of human immunodeficiency virus, hepatitis B, - hepatitis C transmission, arboviruses such as dengue, chikungunya, - the West Nile virus remain significant risks especially during outbreaks. We report a rare case of dengue documented to be acquired through a blood transfusion, which resulted in severe thrombocytopenia prolonging admission in hospital in a neurosurgical patient. The donor of one of the units of red blood cells presented with dengue fever 2 days after donating. Sanger sequencing confirmed DENV-2 (dengue virus, Serotype 2) in both the donor - the patient samples - showed 100% nucleotide sequence identity between the two viruses, confirming transfusion-transmitted dengue infection. This case highlights the importance of arboviral screening of donor blood, especially for populations in endemic areas during outbreaks.

Imprenta: Transfusion, v. 55, n. 7, p. 1655-1661, 2015

Identificador do objeto digital: 10.1111/trf.13054

Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Cell ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue

Data de publicação: 2015

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