Autor(es): Rajapakse Senaka, Rodrigo Chathuraka, Rajapakse Anoja

Resumo: Chikungunya fever is a viral infection transmitted to humans by the bite of infected mosquitoes. Typical chikungunya virus (CHIKV) infection results in an acute febrile illness characterized by severe joint pain - rash. Although chikungunya is generally not considered life threatening, atypical clinical manifestations resulting in significant morbidity have been documented, especially during epidemics. This review describes atypical manifestations following CHIKV infection reported in the literature, categorized as neurological, cardiovascular, skin, ocular, renal - other manifestations. The importance of vertical transmission from an infected mother resulting in neonatal infection is also highlighted. CHIKV infection can result in severe illness needing intensive care, with significant mortality. While there are many deaths reported which are directly attributable to CHIKV infection, background mortality is also increased during epidemics. In this context, considering CHIKV infection a benign - non fatal illness has to be revisited.

Palavras-Chave: Chikungunya; Atypical manifestations; Encephalitis; Myocarditis; Mortality; Review

Imprenta: Transactions of the Royal Society of Tropical Medicine & Hygiene, v. 104, n. 2, p. 89-96, 2010

Identificador do objeto digital: 10.1016/j.trstmh.2009.07.031

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2010

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