Autor(es): Babu Kalpana, Adiga Madhura, Govekar Sunil R, Kumar Bv Ravi, Murthy Krishna R

Resumo: The purpose of this study is to look for any possible associations in 58 consecutive cases of Fuchs heterochromic iridocyclitis (FHI) in a South Indian patient population. Fifty-eight consecutive cases (59 eyes) of FHI underwent a detailed ocular - systemic evaluation. Routine laboratory investigations for uveitis including serum angiotensin-converting enzyme - enzyme-linked immunosorbent assay (ELISA) for toxoplasmosis (IgG - IgM) were done in all the cases. Syndrome Evaluation System comprising of multiplex nucleic acid amplification - signature specific hybridization on the aqueous fluid was done in all 59 eyes for herpes simplex virus (HSV), varicella zoster virus, cytomegalovirus (CMV), rubella virus, chikungunya virus, Toxoplasma, - Mycobacterium tuberculosis. The results were statistically assessed using the SPSS (version 15) package. Thirty-three males - 25 females with FHI were included in the study. Systemic sarcoidosis was seen in two cases. Serological tests failed to confirm an association with toxoplasmosis in all the cases. Aqueous fluid analysis showed positivity only to HSV (one case), CMV (one case), - chikungunya virus (one case). We do see associations of sarcoidosis, HSV, - CMV in FHI in our patient populations as well. The detection of chikungunya virus in a patient with FHI in our series adds to the list of associations with FHI.

Imprenta: Journal of Ophthalmic Inflammation and Infection, v. 3, n. 1, p. 14, 2013

Identificador do objeto digital: 10.1186/1869-5760-3-14

Descritores: Chikungunya virus - Inflammation ; Chikungunya Virus - Virus

Data de publicação: 2013

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