A case of chikungunya fever imported from India to Japan, follow-up of specific IgM and IgG antibodies over a 6-month period
Autor(es): Aoyama Ikuko, Uno Kenji, Yumisashi Takahiro, Takasaki Tomohiko, Lim Chang-Kweng,Kurane Ichiro, Kase Tetsuo, Takahashi Kazuo
Resumo: Chikungunya fever is an arboviral disease caused by chikungunya virus. A 37-year-old Japanese male visited India - developed fever, myalgia, rash, - persisting systemic arthralgia, the latter of which persisted for more than 2 months. The patient was diagnosed with chikungunya fever by virological - serological examinations. In the present study, we followed specific antibody responses over a 6-month period after the onset of the disease. IgM antibody was detected on days 58 - 108, but not on day 137, by enzyme-linked immunosorbent assay. Specific IgG - neutralizing antibodies were detected as late as day 192. The results indicate that specific IgM lasts for 3 to 4 months from the onset of the disease, - that IgG lasts more than 6 months.
Imprenta: Japanese Journal of Infectious Diseases, v. 63, n. 1, p. 65-66, 2010
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever
Data de publicação: 2010
