Autor(es): Robillard Pierre-Yves, Boumahni Brahim, Gérardin Patrick, Michault Alain, Fourmaintraux Alain, Schuffenecker Isabelle, Carbonnier Magali, Djémili Sam, Choker Ghassan, Roge-Wolter Madeleine, Barau Georges

Resumo: In March 2005, an epidemic of chikungunya virus began in the southern portion of Reunion Isl- (French overseas district in the Indian Ocean) - spread to the northern part of the isl- at the end of 2005. The Reunion-South Hospital Group observed the first cases of pregnant women infected with the virus in June 2005. We report here for the first time maternal-fetal transmission of this virus. From June 2005 through the end of January 2006, 84 pregnant women had acute chikungunya infections during pregnancy. In 88% of these cases (n=74)--all involving infections relatively distant from delivery--the newborns appeared asymptomatic. Conversely, 10 newborns had severe attacks (4 with meningoencephalitis - 3 with intravascular coagulations) after birth - required prolonged neonatal hospitalization (6 in the neonatal intensive care unit with intubation - assisted ventilation). No infants died, but there was one case of severe intracerebral hemorrhage after severe thrombocytopenia. These cases were confirmed by specific serology testing or PCR or both for mothers - newborns. We note that all severe cases involved women with viremia - fever in the intrapartum period.

Imprenta: La Presse Me?dicale, v. 35, n. 5, Pt 1, p. 785-788, 2006

Identificador do objeto digital: 10.1016/S0755-4982(06)74690-5

Descritores: Chikungunya virus - Pathogenesis; Chikungunya virus - Serology; Chikungunya virus - Viral infections; Chikungunya virus - Serology; Chikungunya Virus - Virus; Chikungunya virus - Transmission; Chikungunya virus - Chikungunya fever; Chikungunya virus - Epidemic; Chikungunya virus - Epidemiology; Chikungunya virus - Public health

Data de publicação: 2006

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