The expansion of vector-borne diseases and the implications for blood transfusion safety: The case of West Nile Virus, dengue and chikungunya
Autor(es): Paty M-C
Resumo: Arbovirus infections are increasing in prevalence worldwide. This presents new risks for blood transfusion. This article describes the epidemiology - surveillance of West Nile Virus, dengue - chikungunya - their role in the risk management of transfusions. Arboviruses are RNA viruses - very adaptable by nature. The majority of arbovirus infections are zoonoses. The risk of transmission is multifactorial - concerns the virus, vectors, animal reservoirs, the environment - human behaviour. In recent years, West Nile Virus has become established - widespread in North America, the number of cases of dengue worldwide has increased dramatically, - major epidemics of chikungunya have occurred in the Indian Ocean - Asia. The transmission of dengue - chikungunya is demonstrated in temperate zones. All arboviruses are potentially transmissible by transfusion due to their capacity to induce an asymptomatic viremic phase. The risk of West Nile Virus transmission via transfusion is recognised - prevention measures are well established. The risk of transmission via transfusion of dengue - chikungunya is real but difficult to quantify - the optimum prevention strategy is currently the subject of research. Access to up-to-date epidemiological data is an essential aid to decision-making, especially for donors returning from endemic areas to Europe. The challenge is to define - implement appropriate measures in unpredictable situations.
Palavras-Chave: Blood transfusion; West Nile virus; Dengue; Chikungunya; Epidemiology
Imprenta: Transfusion Clinique et Biologique, v. 20, n. 2, p. 165-173, 2013
Identificador do objeto digital: 10.1016/j.tracli.2013.03.008
Descritores: Chikungunya virus - Arbovirus; Chikungunya virus - Pathogenesis; Chikungunya virus - RNA; Chikungunya virus - Infectious diseases; Chikungunya virus - Inflammation; Chikungunya virus - Viral infections; Chikungunya Virus - Virus; Chikungunya virus - Transmission; Chikungunya virus - Chikungunya fever; Chikungunya virus - Dengue; Chikungunya virus - Epidemic; Chikungunya virus - Epidemiology; Chikungunya virus - Public health
Data de publicação: 2013
