Autor(es): Ernould S, Walters H, Aless-ri J-L, Llanas B, Jaffar M-C, Robin S, Attali T, Ramful D, Combes J-C

Resumo: During the southern-hemispheric 2005-2006 summer, Reunion Isl- was struck by an epidemic of Chikungunya (Chik), which affected more than a third of the overall population. Our objective was to describe pediatric cases of Chick. We conducted a retrospective descriptive monocentric study of confirmed pediatric cases of Chik recruited at Saint-Denis' departmental hospital during the peak of the epidemic (January 1st to April 30th 2006). Eighty-six children aged 10 days to 18 years were included. In addition to the typical clinical presentation, we observed other phenotypes. Well-known complicated forms with neurologic, cardiac, gastro-intestinal (plus dehydration) involvement were thoroughly investigated using modern medical technology. We observed 2 fatal cases of acute disease in 9-year-old children: death resulted from a central nervous system insult in one case, - multisystemic neurological, cardiac, haemorrhagic involvement in another. Severe acute presentations requiring hospital admission involved mainly children aged less than 6 months, - those with cardiac, skin - neurologic impairment. The study identified 3 cases of epidermolysis bullosa, which to our knowledge, have never been described previously. Chik in children warrants further research in order to propose early - appropriate treatments to avoid complications.

Imprenta: Archives de Pe?diatrie, v. 15, n. 3, p. 253-262, 2008

Identificador do objeto digital: 10.1016/j.arcped.2007.10.019

Descritores: Chikungunya virus - Pathogenesis; Chikungunya virus - Viral infections; Chikungunya Virus - Virus; Chikungunya virus - Epidemic; Chikungunya virus - Epidemiology; Chikungunya virus - Public health

Data de publicação: 2008

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