Autor(es): Kiviranta, J.; Namikoshi, M.; Sivonen, K.; Evans, W. R.; Carmichael, W. W.; Rinehart, K. L.

Resumo: A new hepatotoxic microcystin was isolated from the cyanobacterium Microcystis aeruginosa strain 205. Its structure was found to be (Dha super(7))microcystin-RR as determined by amino acid analysis, mass spectrometry and super(1)H NMR spectroscopy. LD sub(50) value (i.p. mouse) of this toxin was 180 mu g/kg. The 48 hr lethal concentration (48-hr-LC sub(50)) of the toxin for larvae of the yellow fever mosquito, Aedes aegypti , was 14.9 mu g/ml.

Palavras-Chave: Aedes aegypti; Cyanophyta; Microcystis aeruginosa; Amino acid composition; Biological control; Biological poisons; Larvae; Mice; Microcystin-RR; Structure; Toxicity

Imprenta: Toxicon, v. 30, n. 9, p. 1093-1098, 1992.

Descritores: Aedes aegypti - Cell ; Aedes aegypti - Proteins

Data de publicação: 1992

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