Population genetics and phylogeography of Aedes aegipti (Diptera : Culicidae) from Brazil
Autor(es): Scarpassa, Vera Margarete; Cardoza, Tatiana Bacry; Cardoso, Rubens P., Jr.
Resumo: Population genetic analyses were conducted using samples of Aedes aegypti from 14 localities in the north, southeast, northeast, and central regions of Brazil. An 852-bp region of the mitochondrial DNA cytochrome oxidase I (COI) gene was used in the analyses. Ten haplotypes were observed, and cluster analyses revealed 2 groups (lineages) separated by 8 fixed mutations, suggesting that the Brazilian Ae. aegypti populations probably came from East and West Africa, with evidence of multiple introductions, one related to Group 1 and two related to Group 2. Considering all samples, genetic and geographic distances were significantly correlated (r(2) = 0.332; P = 0.038), supporting the isolation by distance (IBD) model, but no correlation was detected for any particular region, which is consistent with human migrations and trade exchanges. Genetic distances (pairwise F-ST and Nm values), AMOVA, and cluster analyses indicated a deep genetic structure for the Brazilian Ae. aegypti, probably resulting from several factors: multiple introductions associated with distinct lineages, geographic differentiation (IBD), passive dispersal patterns, control activities, extinction and recolonization events, and genetic drift.
Palavras-Chave: Aegypti diptera; Mitochondrial DNA; Microsatellite markers; Enzymatic variability; Natural populations; Breeding structure; Statistical tests; Dengue vector; Differentiation; Albopictus
Imprenta: American Journal of Tropical Medicine and Hygiene, v. 78, n. 6, p. 895-903, 2008
Descritores: Aedes aegypti - DNA ; Aedes aegypti - Public health
Data de publicação: 2008
