Autor(es)Karunaratne, V; Wickramasinghe, A; Herath, AMC; Amarasinghe, PH; Karunaratne, SHPP; Rajapakse, G

ResumoPorphyrins; when photosensitized, transfer their energy/electron to the triplet ground state oxygen, producing cell-lethal reactive oxygen species. Dengue is a tropical disease and the causative viruses are maintained in a cycle involving humans and the principal urban mosquito vector, Aedes aegypti. Infection with dengue virus causes a spectrum of clinical illnesses, ranging from a nonspecific viral syndrome to severe and fatal haemorrhagic disease. In this communication we report on the promising photodynamic effect of porphyrin-generated singlet oxygen on the larvae of A. aegypti, with possible applications in controlling the dengue vector.

Palavras-ChaveSinglet oxygen; Hematoporphyrin; Water; Azide

ImprentaCurrent Science, v. 89, n. 1, p. 170-173, 2005

DescritoresAedes aegypti - Cell ; Aedes aegypti - Dengue

Data de Publicação:2005