Chemistry and bioactivity of physciaceae lichens Pyxine consocians and Geterodermia leucomelos

Autor(es): Kathirgamanathar, S; Ratnasooriya, WD; Baekstrom, P; Andersen, RJ; Karunaratne, V


Resumo: Cabraleadiol monoacetate, atranorin, methyl-beta-orcinolcarboxylate, zeorin, 4- O-methylcryptochlorophaeic acid, and lichexanthone were isolated from the lichen Pyxine consocians Vainio . Heterodermia leucomelos (L). Poelt contained a new triterpenoid, 6 alpha-hydroxyhop-21 beta H-22(29)-en, along with atranorin, zeorin, glyceryl trilinolate, and 3,6-dimethyl-2-hydroxy-4-methoxybenzoic acid. Cabraleadiol monoacetate, 4-O-methylcryptochlorophaeic acid, lichexanthone, and 3,6-dimethyl-2-hydroxy-4-methoxybenzoic acid showed mosquito larvicidal activity against the second instar larvae of Aedes aegypti . Lichexanthone exhibited human sperm motility enhancing activity.


Palavras-Chave: Bioactivity; Heterodermia leucomelos; Lichen; Lichen metabolites; New triterpenoid; Physciaceae; Pyxine consocians


Imprenta: Pharmaceutical Biology, v. 44, n. 3, p. 217-220, 2006


Identificador do objeto digital: 10.1080/13880200600686624


Descritores: Aedes aegypti - Larvicide


Data de publicação: 2006