Autor(es): Cook, Peter E.; McGraw, Elizabeth A.

Resumo: Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

Palavras-Chave: Biological control; Disease control; Pest control; Hosts; Pathogens; Defence mechanisms; Aquatic insects; Disease transmission; Public health; Reviews; Vectors; Immune response; Infection; Dengue virus; Wolbachia pipientis; Plasmodium; Aedes aegypti; Wolbachia; Nematoda

Imprenta: Trends in Parasitology, v. 26, n. 8, p. 373-375, 2010.

Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Virus ; Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Immunology ; Aedes aegypti - Public health

Data de publicação: 2010