Genetic differentiation of Aedes aegypti (Diptera: culicidae), the major dengue vector in Brazil
Autor(es): Ayres, C.; Melo-santos, M.; Sole-Cava, A.; Furtado, A.
Resumo: In 2000, Brazil reported 180,137 cases of dengue, approximately 80% of the total in the Americas. However, little is known about gene flow among the vector populations in Brazil. Random amplified polymorphic DNA (RAPD) was used to study the genetic structure of Aedes aegypti in 15 populations from five states, with a range extending 2,800 km. An analysis of 47 polymorphic RAPD loci estimated gene flow at the macro- (different states) and micro- (different cities) geographical levels. Genetic polymorphism was high (H S = 0.274), and high levels of genetic differentiation existed both between different states (G ST = 0.317) and between cities or neighborhoods in each state (G ST = 0.085-0.265). These values are higher than those described for any other populations of A. aegypti .
Palavras-Chave: Biological vectors; Population genetics; Genetic diversity; Biopolymorphism; Public health; Differentiation; Random amplified polymorphic DNA; Genetic structure
Imprenta: Journal of Medical Entomology, v. 40, n. 4, p. 430-435, 2003.
Descritores: Aedes aegypti - DNA ; Aedes aegypti - Virus ; Aedes aegypti - Dengue ; Aedes aegypti - Public health
Data de publicação: 2003
