Development and evaluation of emulsions from Carapa guianensis (Andiroba) oil
Autor(es): Ferreira, Magda R. A.; Santiago, Rosilene R.; de Souza, Tatiane P.; Egito, Eryvaldo S. T.; Oliveira, Elquio E.; Soares, Luiz A. L.
Resumo: Carapa guianensis, a popular medicinal plant known as 'Andiroba' in Brazil, has been used in traditional medicine as an insect repellent and anti-inflammatory product. Additionally, this seed oil has been reported in the literature as a repellent against Aedes aegypti. The aim of this work is to report on the emulsification of vegetable oils such as 'Andiroba' oil by using a blend of nonionic surfactants (Span 80? and Tween 20?), using the critical hydrophilic--lipophilic balance (HLB) and pseudo-ternary diagram as tools to evaluate the system's stability. The emulsions were prepared by the inverse phase method. Several formulations were made according to a HLB spreadsheet design (from 4.3 to 16.7), and the products were stored at 25?C and 4?C. The emulsion stabilities were tested both long- and short-term, and the more stable one was used for the pseudo-ternary diagram study. The emulsions were successfully obtained by a couple of surfactants, and the HLB analysis showed that the required HLB of the oil was 16.7. To conclude, the pseudo-ternary diagram identified several characteristic regions such as emulsion, micro-emulsion, and separation of phases.
Palavras-Chave: Seeds; Repellents; Pest control; Surfactants; Aquatic insects; Emulsions; Vegetables; Stored products; Medicinal plants; Emulsification; Inflammation
Imprenta: AAPS PharmSciTech, v. 11, n. 3, p. 1383-1390, 2010.
Descritores: Aedes aegypti - Inflammation ; Aedes aegypti - Repellent
Data de publicação: 2010
