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Engineering the control of mosquito-borne infectious diseases

Autor(es)Gabrieli, Paolo; Smidler, Andrea; Catteruccia, Flaminia
ResumoRecent advances in genetic engineering are bringing new promise for controlling mosquito populations that transmit deadly pathogens. Here we discuss past and current efforts to engineer mosquito strains that are refractory to disease transmission or are suitable for suppressing wild disease-transmitting populations.
Palavras-ChaveYellow-fever mosquito; Plasmodium-falciparum development; Anopheles-stephensi mosquitos; Piggybac transposable element; Malaria vector mosquito; Gene drive system; Aedes-Aegypti; Homing endonucleases; Transgenic mosquitos; Germline transformation
ImprentaGenome Biology, v. 15, n. 11, 2014
Identificador do Objeto Digital10.1186/s13059-014-0535-7
DescritoresAedes aegypti - Public health
Data de Publicação:2014