Engineering the control of mosquito-borne infectious diseases
Autor(es): Gabrieli, Paolo; Smidler, Andrea; Catteruccia, Flaminia
Resumo: Recent advances in genetic engineering are bringing new promise for controlling mosquito populations that transmit deadly pathogens. Here we discuss past and current efforts to engineer mosquito strains that are refractory to disease transmission or are suitable for suppressing wild disease-transmitting populations.
Palavras-Chave: Yellow-fever mosquito; Plasmodium-falciparum development; Anopheles-stephensi mosquitos; Piggybac transposable element; Malaria vector mosquito; Gene drive system; Aedes-Aegypti; Homing endonucleases; Transgenic mosquitos; Germline transformation
Imprenta: Genome Biology, v. 15, n. 11, 2014
Identificador do objeto digital: 10.1186/s13059-014-0535-7
Descritores: Aedes aegypti - Public health
Data de publicação: 2014
