2'-branched nucleosides for treatment of viral infections

Autor(es): Novartis AG; Yokokawa, Fumiaki


Resumo: The present invention provides a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is defined herein, which is a 2?-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue virus, yellow fever virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus.


Imprenta: US2014/65101 A1, 2014


Descritores: Zika virus - Viral infections ; Zika virus - Zika fever ; Zika virus - Dengue


Data de publicação: 2014