Hemocyte cell surface changes in Aedes aegypti in response to microfilariae of Dirofilaria immitis.

Autor(es): Nappi A J; Christensen B M


Resumo: This study involved the assessment of surface changes on hemocytes of Aedes aegypti black-eyed Liverpool strain in association with the melanization response against intrathoracically inoculated Dirofilaria immitis microfilariae (mff). Surface changes on hemocytes were identified using fluorescein-labeled wheat germ agglutinin (WGA). In mosquitoes eliciting a melanization response against inoculated mff, there was a 5-fold increase in the percentages of hemocytes exhibiting WGA binding compared with saline inoculated controls. Relationships of this hemocyte activation in relation to cell-mediated melanization responses of adult mosquitoes against mff are discussed.


Palavras-Chave: Hemocytes; Mosquitos; Microfilariae; Melanization; Blood cells; Parasites; Parasite hosts; Insect vectors


Imprenta: The Journal of Parasitology, v. 72, n. 6, p. 875-879, 1986


Descritores: Aedes aegypti - Cell ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - Immunology


Data de publicação: 1986