Autor(es): de Pedro-Cuesta J.; Abraira V.; Jiang G. X.; Solders G.; Fredrikson S.

Resumo: Using hierarchical cluster analysis, applied to 47 cases of Guillain-Barré Syndrome (GBS) incident in South-West Stockholm (SWS) during the period from January 1973 to June 1992, we identified three major clinicoepidemiological subgroups. The first subgroup, 25.5% of the cases (26.7 +/- 6.7 years), recorded a peak incidence at ages 20-29 years and presented significant differences from other subgroups, a high proportion of cases with onset at low age preceded by respiratory infection (83.3%) and with normal motor conduction velocity (50.0%). Also found, were less affected biological parameters, a rapidly progressive course and independence in gait at one month after onset. A second subgroup, 27.7% of cases, was severely affected, clinically and functionally. It consisted predominantly of young individuals (22.7 +/- 11.1 years), with a high incidence (69.2% of cases) in autumn. A third subgroup, comprising 40.4% of cases, was older (61.1 +/- 11.0 years) and, in general, also severely affected. The incidence of this form appeared to be invariant with time.

Imprenta: Acta Neurologica Scandinavica, v. 93, n. 2-3, p. 175-183, 1996

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Epidemiology ; Guillain-Barre Syndrome - Public health

Data de publicação: 1996

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