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BiPAP in early guillain-barré syndrome may fail.

Autor(es)Wijdicks Eelco F M,Roy Tuhin K
ResumoNon-invasive mechanical ventilation (BiPAP) has been introduced for use in neuromuscular respiratory disease such as amyotrophic lateral sclerosis and myasthenia gravis. There is no experience in Guillain-Barré syndrome. We describe for the first time the use of BiPAP to assist in the work of breathing in two consecutive patients with progressing Guillain-Barré syndrome (GBS) and marginal pulmonary function. Our initial attempts to use BiPAP in GBS and early neuromuscular respiratory failure were totally unsuccessful. There was marked initial improvement; however, emergency intubation was needed in both patients, one of which became acutely cyanotic. Until more experience is available, we strongly warn against using BiPAP in deteriorating patients with GBS.
ImprentaThe Canadian Journal of Neurological Sciences. Le Journal Canadien des Sciences Neurologiques, v. 33, n. 1, p. 105-106, 2006
Identificador do Objeto Digital10.1017/S0317167100004790
DescritoresGuillain-Barre Syndrome - Pathogenesis
Data de Publicação:2006