Autor(es): Goeijenbier M,Slobbe L,van der Eijk A,de Mendonça Melo M,Koopmans M P G,Reusken C B E M

Resumo: Zika virus (ZIKV), a mosquito-borne flavivirus closely related to yellow fever virus and dengue virus, is currently causing a large outbreak in the Americas. Historically, ZIKV infection was considered a sporadic, relatively mild disease characterised by fever, maculopapular rash, conjunctivitis and often arthralgia. However, current observational studies suggest that ZIKV may cause more severe neurological sequelae such as Guillain-Barre syndrome, and birth defects, mainly microcephaly, in babies of whom the mother was infected with ZIKV during pregnancy. This article provides a clinically focussed overview of ZIKV, with emphasis on the current outbreak, clinical manifestations, diagnostic tools and caveats.

Palavras-Chave: Zika virus; Microcephaly; Flavivirus; Aedes; Outbreak; Americas

Imprenta: The Netherlands Journal of Medicine, v. 74, n. 3, p. 104-109, 2016

Descritores: Guillain-Barre Syndrome - Dengue ; Guillain-Barre Syndrome - Microcephaly ; Guillain-Barre Syndrome - Rash maculopapular ; Guillain-Barre Syndrome - Zika fever

Data de publicação: 2016

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