Miller-Fisher syndrome associated with chronic lymphocytic leukemia.
Autor(es): Aki Zeynep,; Aksoy Ozlem; Sucak Gulsan; Kuruo?lu Reha; Ya?ci Münci
Resumo: Chronic lymphocytic leukemia (CLL) is a frequent hematological malignancy, with meningeal or peripheral nerve infiltrations being the most commonly encountered neurological complications. In this report, we describe a CLL patient with Miller-Fisher syndrome (MFS) who responded to immune modulation with plasmapheresis. A 47-year-old man diagnosed as B-cell CLL admitted with neutropenic fever. He complained of diplopia and numbness of both arms. Neurological examination revealed a bilateral external ophthalmoplegia, dysphagia, dysarthria, mild shoulder girdle muscle weakness and gait ataxia, accompanied by absent tendon reflexes. Nerve conduction studies were indicative of a predominantly axonal sensori-motor peripheral neuropathy. This association of CLL with MFS had not been previously reported in the literature.
Imprenta: Neurology India, v. 56, n. 2, p. 198-200, 2008
Identificador do objeto digital: 10.4103/0028-3886.42003
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Public health
Data de publicação: 2008
