Pain in central and peripheral demyelinating disorders.
Autor(es): Moulin D. E.
Resumo: Moderate to severe pain is a common feature of central and peripheral demyelinating disorders. Pain in multiple sclerosis tends to occur when the disease is well-established and usually lingers infinitely. Pain in Guillain-Barré syndrome tends to be particularly severe at the time of initial presentation and usually resolves over 8 to 12 weeks. Pain in both conditions is generally caused by either the direct effects of nerve injury or the result of paralysis and prolonged immobilization. Pain syndromes are well-defined in each disorder based on the underlying pathophysiology. Treatment involves a variety of pharmacologic and nonpharmacologic approaches individualized for each specific pain syndrome.
Imprenta: Neurologic Clinics, v. 16, n. 4, p. 889-898, 1998
Identificador do objeto digital: 10.1016/S0733-8619(05)70103-1
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Clinical examination
Data de publicação: 1998
