Progressive subacute Miller-Fisher syndrome successfully treated with plasmapheresis.
Autor(es): Ejma Maria; Waliszewska-Prosó? Marta; Hofman Anna; Budrewicz S?awomir; Podemski Ryszard; Bili?ska Ma?gorzata; Koszewicz Magdalena
Resumo: Miller-Fisher Syndrome (MFS) is a rare acute polyneuropathy composed of the clinical triad of ataxia, areflexia and ophthalmoplegia, with a monophasic, self-limited course and spontaneous improvement. The authors present a 65-year-old man with Miller-Fisher syndrome consisting of bilateral ophthalmoplegia, trigeminal and facial nerve palsy, mild ataxia and peripheral neuropathy. The disease had a progressive, subacute course within 3 months. A high titer of anti-GQ1b antibodies was detected. As a result of plasmapheresis, complete recovery was achieved. The presented case was atypical in its clinical course and treatment. It could support the theory of the continuity between MFS, Bickerstaff brainstem encephalitis (BBE), and Guillain-Barré syndrome (GBS).
Palavras-Chave: Anti-GQ1b antibody, Miller-Fisher syndrome, Plasmapheresis
Imprenta: Neurologia i Neurochirurgia Polska, v. 49, n. 2, p. 137-138, 2015
Identificador do objeto digital: 10.1016/j.pjnns.2015.03.002
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2015
