Vindesine-induced neuropathy mimicking Guillain-Barré syndrome

Autor(es): Liu Lihui,Shi Bing,Ye Liping,Jin Jiangang,Zhang Yuzhu,Hu Wenqing,Liu Mingjuan,Li Guojian


Resumo: A 13-year-old girl with acute lymphoblastic leukaemia, who was being treated with chemotherapy (including vindesine), developed paraplegia without paresthesia, which mimic Guillain-Barré syndrome. Spinal fluid analysis showed a normal protein level, vindesine neuropathy seemed to be the cause of the patient's neurological symptoms. The patient seemed to benefit from human normal immunoglobulin therapy and recovered 4 weeks later.


Palavras-Chave: Vindesine; Acute lymphoblastic leukemia; Neuropathy; Guillain-Barré syndrome


Imprenta: Leukemia Research, v. 33, n. 12, p. e232-e233, 2009


Identificador do objeto digital: 10.1016/j.leukres.2009.04.014


Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis


Data de publicação: 2009