Autor(es): Weiner L P,Fleming J O

Resumo: Neurotropic viruses cause a number of important infectious syndromes including encephalitis, myelitis, meningitis, and radiculopathy. In this review, the biology of conventional and unconventional viruses is examined. The host immune response to viruses is discussed, and patterns of viral pathogenesis are explained. The clinical features, laboratory findings, management of important viral infections, such as herpes simplex encephalitis and epidemic encephalitis, are presented. Post-infection syndromes, such as the Guillain-Barré syndrome, and chronic viral infections, such as those causing progressive multifocal leukoencephalopathy and subacute sclerosing panencephalitis, are discussed. Current knowledge concerning the nature of unconventional virus-like agents of the spongiform encephalopathies, including kuru and Creutzfeldt-Jakob disease, is summarized. Finally, viral infections of immunocompromised patients and the possible role of viruses in the newly described acquired immunodeficiency syndrome (AIDS) are examined.

Palavras-Chave: Encephalitis; Post-infection syndrome; Unconventional virus; Acquired immunodeficiency syndrome; Subacute sclerosing panencephalitis; Progressive multifocal leukoencephalopathy

Imprenta: Journal of Neurosurgery, v. 61 ,n. 2, p. 207-224, 1984

Identificador do objeto digital: 10.3171/jns.1984.61.2.0207

Descritores: Guillain-Barre Syndrome - Arbovirus ; Guillain-Barre Syndrome - DNA ; Guillain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - RNA ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Infectious diseases ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Epidemic ; Guillain-Barre Syndrome - Immunology

Data de publicação: 1984

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