Systemic lupus erythematosus presenting with neurological disorders

Capa:Systemic lupus erythematosus presenting with neurological disorders

Autor(es): Tola M R,Granieri E,Caniatti L,Paolino E,Monetti C,Dovigo L,Scolozzi R,De Bastiani P,Carreras M


Resumo: Six patients are described who developed a wide variety of neurological manifestations heralding systemic lupus erythematosus (SLE), which included epileptic seizures, stroke, peripheral polyradiculoneuropathy similar to Guillain-Barré syndrome, transverse myelopathy and multifocal disorders with remitting course mimicking multiple sclerosis. The peculiarity of these cases was that the neurological disorders remained the only manifestations of SLE for many years and the nervous system appeared to be the main target even after the development of systemic SLE. In five patients the prognosis was favourable and corticosteroid treatment led to prolonged remission.


Palavras-Chave: Nervous system involvement; Systemic lupus erythematosus; Cerebrospinal fluid; Magnetic resonance imaging


Imprenta: Journal of Neurology, v. 239, n. 2, p. 61-64, 1992


Identificador do objeto digital: 10.1007/BF00862972


Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies


Data de publicação: 1992