Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies.
Autor(es): Kwa M. S.; van Schaik I. N.; Brand A.; Baas F.; Vermeulen M.
Resumo: We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barré syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0).
Imprenta: Journal of Neuroimmunology, v. 116, n. 2, p. 220-225, 2001
Identificador do objeto digital: 10.1016/S0165-5728(01)00307-1
Descritores: Guillain-Barre Syndrome - Cell ; illain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Serological diagnosis ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2001
