Meningitis determined by oligosymptomatic dengue virus type 3 infection: report of a case.
Autor(es): Soares C. N.; Cabral-Castro M. J.; Peralta J. M.; Freitas M. R. G.; Puccioni-Sohler M.;
Resumo: Dengue infection is a mosquito-borne disease caused by a flavivirus, and is recognized in over 100 countries with 2.5 billion people living in areas of risk. Neurological manifestations such as encephalitis, myelitis, Guillain-Barré syndrome, cranial nerve palsies, neuromyelitis optica, and encephalomyelitis have been recognized as clinical consequences of dengue infection. Meningitis is a rare complication. We report the case of a 24-year-old woman who presented with fever, headache, and nuchal rigidity without the typical symptoms of dengue infection. Cerebrospinal fluid analysis showed lymphocytic pleocytosis with a normal glucose value and negative bacterial and fungal cultures. The etiology of meningitis was confirmed by positive dengue PCR in the serum. This case report highlights dengue infection as a potential cause of meningitis in endemic areas. Also, meningitis can be the first manifestation of the infection. Dengue should be investigated even in the absence of a typical picture of the infection.
Imprenta: International Journal of Infectious Diseases, v. 14, n. 2, p. 150-152, 2010
Identificador do objeto digital: 10.1016/j.ijid.2009.03.016
Descritores: Guillain-Barre Syndrome - Flaviviridae ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Viral infections ; Guillain-Barre Syndrome - RT-PCR ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Dengue
Data de publicação: 2010