Specific genetic features of Campylobacter jejuni strain G1 revealed by genome sequencing
Autor(es): Lehri Burhan,Kukreja Kushneet,Vieira Ana,Zaremba Milena,Bonney Kwasi,Karlyshev Andrey V
Resumo: This report describes a draft genome sequence of Campylobacter jejuni strain G1. The strain contains no plasmids, despite being resistant to tetracycline (Tet). Comparison of the genome of this strain with that of a reference strain NCTC 11168 (Tet sensitive) revealed the presence of a candidate gene that may be responsible for antibiotic resistance, as well as the genes involved in the synthesis of ganglioside-mimicking molecules responsible for the development of a neurodegenerative disorder, Guillain-Barré syndrome.
Palavras-Chave: Guillaine-Barré syndrome; Ganglioside mimicry; Lipo-oligosaccharide; Multidrug efflux pump; Tetracycline resistance
Imprenta: FEMS Microbiology Letters, v. 362, n. 4, p. 1-3, 2015
Identificador do objeto digital: 10.1093/femsle/fnu064
Descritores: Guillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - DNA ; Guillain-Barre Syndrome - Genome ; Guillain-Barre Syndrome - Molecular Structure ; Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 2015
