Autor(es): Tsang Raymond Sw; Valdivieso-Garcia Alfonso

Resumo: Guillain-Barre syndrome is a postinfectious disorder caused by an aberrant immune response to an infectious pathogen, resulting in an autoimmune disease. As with other autoimmune diseases of infectious nature, the intricate balance of the numerous factors involved in the immune response may determine the outcome of the interaction between the microbe and host. Recent studies focusing on the role of cytokines and its network of related mediators and receptors suggest that any imbalance may make a significant contribution to the outcome of the infectious disease process. Better understanding of the pathogenesis of Guillain-Barre syndrome may lead to the discovery of newer therapeutics and may also serve as a model for studying other autoimmune diseases.

Imprenta: Expert Review of Anti-Infective Therapy, v. 1, n. 4, p. 597-608, 2003

Identificador do objeto digital: 10.1586/14787210.1.4.597

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins Guillain-Barre Syndrome - Autoimmunity ; Guillain-Barre Syndrome - Cytokines ; Guillain-Barre Syndrome - Infectious diseases ; Guillain-Barre Syndrome - Vaccine Guillain-Barre Syndrome - Immunology

Data de publicação: 2003

INDICADORES

ACESSO