Autor(es): Vermeersch G,Boschi A,Deggouj N,van Pesch V,Sindic C J M

Resumo: We describe a patient who had four relapses of Miller Fisher syndrome over a period of 20 years. The classical triad - ophthalmoparesis, ataxia and areflexia - was present during the first two attacks; ataxia was not observed during the third episode. The final recurrence was characterized by signs suggestive of a central involvement of the oculomotor pathways, subclinical slowing of the visual-evoked potentials, and peripheral vestibular hyporeactivity. Brain imaging was normal, but high levels of anti-GQ1b IgG antibodies were detectable during the second relapse and persisted after the fourth recurrence despite complete clinical recovery.

Palavras-Chave: Miller Fisher syndrome; Anti-GQ1b lgG antibodies; Visual saccades; Vestibular hyporeactivity

Imprenta: European Neurology, v. 66, n. 4, p. 210-214, 2011

Identificador do objeto digital: 10.1159/000331486

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Antibodies

Data de publicação: 2011