Neurology and the lupus anticoagulant.
Autor(es): Englert H.; Derue G.; Hughes G. R.
Resumo: The lupus anticoagulant, an immunoglobulin of the IgG or IgM class, is one of a group of antiphospholipid antibodies. Although an anticoagulant in vitro, its action in vivo is that of a procoagulant. This procoagulant activity may involve many organ systems including the nervous system. Thus far cerebral thrombosis, spinal thrombosis, chorea and Guillain-Barré syndrome have been described in association with the lupus anticoagulant. Although the lupus anticoagulant is an uncommon cause of neurological disease, it must be considered, especially in a setting of a prolongation of the common pathway of coagulation, thrombosis and other autoimmune phenomena.
Imprenta: European Neurology, v. 24, n. 6, p. 422-425, 1985
Identificador do objeto digital: 10.1159/000115836
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology
Data de publicação: 1985
