Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

Capa:Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

Autor(es): González Pérez P,Serrano-Pozo A,Franco-Macías E,Montes-Latorre E,Gómez-Aranda F,Campos T


Resumo: We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain-Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR-induced acute neurotoxicity may be a challenge for clinicians.


Palavras-Chave: Chemotherapy; Guillain-Barre´syndrome; Leukaemia; Neurotoxicity; Vincristine


Imprenta: European Journal of Neurology, v. 14, n. 7, p. 826-828, 2007


Identificador do objeto digital: 10.1111/j.1468-1331.2007.01842.x


Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Public health


Data de publicação: 2007