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Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

Autor(es)González Pérez P,Serrano-Pozo A,Franco-Macías E,Montes-Latorre E,Gómez-Aranda F,Campos T
ResumoWe report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain-Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR-induced acute neurotoxicity may be a challenge for clinicians.
Palavras-ChaveChemotherapy; Guillain-Barre´syndrome; Leukaemia; Neurotoxicity; Vincristine
ImprentaEuropean Journal of Neurology, v. 14, n. 7, p. 826-828, 2007
Identificador do Objeto Digital10.1111/j.1468-1331.2007.01842.x
DescritoresGuillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Public health
Data de Publicação:2007