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Structure and biology of self lipid antigens

Autor(es)De Libero G,Mori L
ResumoSelf lipid antigens induce selection and expansion of autoreactive T cells which have a role in immunoregulation and disease pathogenesis. Here we review the important biological rules which determine lipid immunogenicity. The impact of lipid structure, synthesis, traffic, membrane distribution and CD1 loading are discussed.
ImprentaCurrent Topics in Microbiology and Immunology, v. 314, p. 51-72, 2007
Identificador do Objeto Digital10.1007/978-3-540-69511-0_3
DescritoresGuillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Immunology
Data de Publicação:2007