Structure and biology of self lipid antigens
Autor(es): De Libero G,Mori L
Resumo: Self lipid antigens induce selection and expansion of autoreactive T cells which have a role in immunoregulation and disease pathogenesis. Here we review the important biological rules which determine lipid immunogenicity. The impact of lipid structure, synthesis, traffic, membrane distribution and CD1 loading are discussed.
Imprenta: Current Topics in Microbiology and Immunology, v. 314, p. 51-72, 2007
Identificador do objeto digital: 10.1007/978-3-540-69511-0_3
Descritores: Guillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Immunology
Data de publicação: 2007
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