Plasma exchange in immune-mediated neuropathies.
Autor(es): Lehmann Helmar C.; Hartung Hans-Peter; Meyer Zu Hörste Gerd; Kieseier Bernd C.
Resumo: Plasma exchange is frequently used for treatment of immune-mediated neuropathies. Here, we review the current value of plasma exchange in the treatment of different forms of immune-mediated neuropathies and discuss latest developments. Plasma exchange is used in various disease conditions; however, of all immune-mediated disorders of the peripheral nerve, Guillain-Barré syndrome represents the disease entity in which short and long-term efficacy, optimal frequency, side effects and cost effectiveness of plasma exchange are best documented. Although randomized trials evaluated the value of plasma exchange in chronic forms of immune-neuropathies, its long-term efficacy and its optimal frequency still remain unclear. Especially in chronic forms of immune-mediated neuropathies, plasma exchange needs to be further evaluated in clinical trials to assess long-term efficacy and its potential as adjuvant treatment option.
Imprenta: Current Opinion in Neurology, v. 21, n. 5, p. 547-554, 2008
Identificador do objeto digital: 10.1097/WCO.0b013e32830b0f61
Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health
Data de publicação: 2008
