Systemic lupus erythematosus and acute demyelinating polyneuropathy
Autor(es): Robson M G,Walport M J,Davies K A
Resumo: Guillain-Barré syndrome has been described only rarely in patients with SLE. In this Grand Round we describe a 33-yr-old patient who presented with features of central nervous system lupus, thrombocytopenia, and a severe haemolytic anaemia. Within a few days of her admission, following the commencement of steroid therapy, and a grand mal seizure, the patient developed paralysis of her lower limbs, due to an acute demyelinating polyneuropathy, and subsequently a retinal vasculitis. We discuss the epidemiological and possible immunopathological links between SLE and Guillain-Barré syndrome, and possible treatment strategies.
Palavras-Chave: Systemic lupus erythematosus; Guillain-Barré syndrome; Polyneuropathy; Retinal vasculitis
Imprenta: British journal of Rheumatology, v. 33, n. 11, p. 1074-1077, 1994
Identificador do objeto digital: 10.1093/rheumatology/33.11.1074
Descritores: Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 1994
