Guillain-Barré syndrome. Increased lymphoproliferative potential.
Autor(es)Birnbaum G.
ResumoPeripheral white blood cells (WBC) from normal persons, patients with Guillain-BarréSyndrome (GBS), and persons with a variety of other neurological diseases were maintained in tissue culture. The WBC from patients with GBS demonstrated a greatly increased tendency to become continuous self-proliferating lines of lymphoblastoid cells. Cell lines from both normal subjects and patients were examined by light and electron microscopy. Herpes-like viral particles were found in both varieties of lines. Epstein-Barr virus antigen was demonstrated in most of the cell lines. Animal inoculations of the cells failed to produce any clinical or morphological alterations in the recipients.
ImprentaArchives of Neurology, v. 28, n. 4, p. 215-218, 1973
Identificador do Objeto Digital10.1001/archneur.1973.00490220023001
DescritoresGuillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Immunology
Data de Publicação:1973
