Guillain-Barré syndrome. Increased lymphoproliferative potential.
Autor(es): Birnbaum G.
Resumo: Peripheral white blood cells (WBC) from normal persons, patients with Guillain-BarréSyndrome (GBS), and persons with a variety of other neurological diseases were maintained in tissue culture. The WBC from patients with GBS demonstrated a greatly increased tendency to become continuous self-proliferating lines of lymphoblastoid cells. Cell lines from both normal subjects and patients were examined by light and electron microscopy. Herpes-like viral particles were found in both varieties of lines. Epstein-Barr virus antigen was demonstrated in most of the cell lines. Animal inoculations of the cells failed to produce any clinical or morphological alterations in the recipients.
Imprenta: Archives of Neurology, v. 28, n. 4, p. 215-218, 1973
Identificador do objeto digital: 10.1001/archneur.1973.00490220023001
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Immunology
Data de publicação: 1973
