Simultaneous human herpesvirus 6-associated encephalitis and Guillain-Barré syndrome in a patient after matched unrelated donor haematopoietic stem cell transplantation

Autor(es): Tomaszewska Agnieszka,Nasilowska-Adamska Barbara,Dzieciatkowski Tomasz,Marianska Bo?ena


Resumo: Viral infections are still a serious diagnostic and therapeutic problem in patients undergoing alternative donor transplants. ?-Herpesviruses (especially human herpesvirus type 5, 6 and 7) are recognized pathogens in this group of patients and may cause central nervous system disease. Guillain-Barré syndrome (GBS) is a very rare complication among stem cell transplant recipients and usually has been attributed to infection. We report a case of resolving simultaneous GBS and HHV-6-associated encephalitis in a haematopoietic stem cell transplant recipient with preceding reactivation of cytomegalovirus (CMV) infection. According to our knowledge this well-documented case is probably the first report from Poland.


Palavras-Chave: Guillain-Barré syndrome; Encephalitis; Haematopoietic stem cell transplant recipients; Human herpesvirus-6


Imprenta: Archives of Medical Science : MAS, v. 6, n. 2, p. 288-290, 2010


Identificador do objeto digital: 10.5114/aoms.2010.13912


Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Viral infections


Data de publicação: 2010