Low-dose oral etidronate therapy for immobilization hypercalcaemia associated with Guillain-Barré syndrome.
Autor(es): Go T.
Resumo: A low dose of oral etidronate (3.7 mg kg(-1) d(-1)) was administered for immobilization hypercalcaemia associated with Guillain-Barré syndrome in a 12-y-old boy. There was a slight increase in osteoblastic bone formation reflected by alkaline phosphatase and in particular bone-specific alkaline phosphatase during the treatment and serum calcium decreased to the normal range within 2 wk. No adverse side effects were observed and the patient's linear growth subsequently progressed. A low dose of oral etidronate is safe and effective for treatment of immobilization hypercalcaemia in children, without inhibiting bone formation.
Imprenta: Acta Paediatrica, v. 90, n. 10, p. 1202-1204, 1992
Identificador do objeto digital: 10.1111/j.1651-2227.2001.tb03256.x
Descritores: Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 2001