Serum antibodies to HTLV-I in human demyelinating disease
Autor(es): Epstein L,Blumberg B,Crowley J,Samuel K,Goudsmit J,Cook S,Dowling P
Resumo: Serum HTLV-I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV-I core protein antigens and an immunoblot assay with E. coli-expressed P21E transmembrane protein was employed to detect antibodies to HTLV-I evelope antigens. No serologic evidence of prior HTLV-I infection in our population of multiple sclerosis (MS) or Guillain-Barré Syndrome (GBS) patients was found.
Palavras-Chave: HTLV-I; Multiple sclerosis; Guillain-Barre syndrome
Imprenta: Acta neurologica Scandinavica, v. 75, n. 4, p. 231-233, 1987
Identificador do objeto digital: 10.1111/j.1600-0404.1987.tb07925.x
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Serology ; Guillain-Barre Syndrome - Virus ; Guillain-Barre Syndrome - Immunology
Data de publicação: 1987
