Autoimmune peripheral nerve diseases following infection
Autor(es): Koga M,Yuki N
Resumo: Guillain-Barré syndrome is an autoimmune peripheral neuropathy that develops as a result of various infections.Campylobacter jejuni , a pathogenic organism of acute enteritis, has been identified as a major pathogen of prior infection . It has been proved that ganglioside which is a constituent component of human peripheral nerve and polypolysaccharide similar in structure exist on the bacterial body and autoantibody which reacts with ganglioside is detected in the patient's blood , Molecular homology hypothesis has been proposed as a mechanism of onset of Guillain-Barré syndrome.
Palavras-Chave: Guillain-Barré syndrome; Molecular homology; Anti -ganglioside antibody
Imprenta: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, v. 90, n. 12, p. 2413-2419.
Identificador do objeto digital: 10.2169/naika.90.2413
Descritores: Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 2001
