Autor(es): Soto V Alvaro,Cartier R Luis

Resumo: Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With the diagnosis of Guillain-Barré syndrome (GBS), he was treated with ivIg. He developed an acute encephalopathy few hours after the administration of ivIg, with a decreased level of consciousness and agitation. A CT scan revealed moderate and diffuse brain edema. Encephalopathy resolved 96 hours after ivIg withdrawal and use of plasma exchange. A CT scan performed seven days after showed the resolution of brain edema.

Palavras-Chave: Guillain-Barré syndrome; Immunoglobulin intravenous; Neurotoxicity syndromes

Imprenta: Revista me?dica de Chile, v. 139, n. 10, p. 1340-1343.

Identificador do Objeto Digital: 10.4067/S0034-98872011001000014

Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies

Data de Publicação: 2011