Autor(es): Boorman J P

Resumo: The original isolation of Uganda S virus was from a pool of 3 species of Aedes mosquitoes [this Bulletin, 1948, v 23, 940] 44% of 207 sera from a village north of Lagos were recently found to have antibody The commonest mosquito there was Aedes aegypti and so its ability to transmit the virus was tested 64 mosquitoes were infected by feeding through an artificial membrane on a mixture of infected mouse brain and blood Their virus content was titrated at intervals, the initial level of 10 57 fell to about 10 -1 on days 1, 2 and 3, then no virus was detected until day 9 when the titre was 10-35 and titres of this oider persisted until day 79 One of these mosquitoes transmitted virus by bite to suckling mice on days 28, 29, 34 and 36 Batches of mosquitoes were fed on different concentrations of virus batches with mean virus contents of 10 18, 10 32 and 10 46 had infection rates of 13, 34 and 53% respectively after 28 days Another batch of mosquitoes with a mean initial virus content of 10-6.9 were tested for their ability to transmit by bite none of 12 transmitted at day 4, 2 of 10 transmitted at day 12, 6 of 9 at day 23, and 90% transmitted at days 39 and 46 These mosquitoes were tested for virus and 95% were found to have been infected Aedes aegypti can therefore be infected with Uganda S virus by feeding and after a short incubation period transmit by bite until at least 46 days after infection C. E. Gordon Smith.

Palavras-Chave: Mosquitores; Viruses

Imprenta: Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 52, n. 4, p. 383-388, 1958

Identificador do objeto digital: 10.1016/0035-9203(58)90053-1

Descritores: Aedes aegypti - virus ; Aedes aegypti - Transmission

Data de publicação: 1958

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