Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205
Autor(es): Kiviranta J,Namikoshi M,Sivonen K,Evans W R,Carmichael W W,Rinehart K L
Resumo: A new hepatotoxic microcystin was isolated from the cyanobacterium Microcystis aeruginosa strain 205. Its structure was found to be [Dha7]microcystin-RR as determined by amino acid analysis, mass spectrometry and 1H NMR spectroscopy. LD50 value (i.p. mouse) of this toxin was 180 micrograms/kg. The 48 hr lethal concentration (48-hr-LC50) of the toxin for larvae of the yellow fever mosquito, Aedes aegypti, was 14.9 micrograms/ml.
Imprenta: Toxicon : Official Journal of the International Society on Toxinology, v. 30, n. 9, p. 1093-1098, 1992
Identificador do objeto digital: 10.1016/0041-0101(92)90054-9
Descritores: Aedes aegypti - Molecular Structure
Data de publicação: 1992
